The term drug resistant bacteria is used in medical practice for characterizing the ability of microscopic organisms to resist high concentrations of various active substances in the body.
Drug resistant bacteria definition can also be understood as the preservation of the protozoa vital processes after antibiotics administration in therapeutic doses.
Antibacterial drugs penetrate well into the body tissues and have a selective effect on the bacterial population. Modern antibiotics interfere with the metabolism, stop the reproduction and kill bacteria without harming the cells, organs or tissues.
Although bacteria lack intelligence, they have their protective mechanisms. This is due to the unique ability of drug resistant bacteria to evolve. Pathogens have two types of drug resistance: acquired and natural (intrinsic).
Natural resistance of bacteria can result from the ability of drugs to penetrate in a bacterial cell, or intrinsic ability of the microorganism to synthesize enzymes that inactivate the antimicrobial agents.
Acquired drug bacterial resistance is associated with their rapid adaptation to environmental conditions. Bacteria are able to mutate rapidly, due to which new strains are formed. These are capable of remaining viable in high concentrations of active substances, which used to be hazardous for them earlier. List of drug resistant bacteria increases every year. It is especially clearly observed in recent decades. Scientists explain this phenomenon by a significant increase in the number of people, using antibiotics.
For example, more and more importance is given to the increase in such drug resistant bacteria, as neisseria gonorrhoeae, staphylococci, pneumococci, and pseudomonas aeruginosa. Diseases, caused by such strains, are characterized by longer and more difficult treatment. Ultimately, it has a great social value and economic damage. People spend more money to the medication, at this time the risks of the spread of new microorganisms strains in the human population increase. The consequences of these bacteria spread are hard to predict.Read More
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