Some of the most common infectious diseases are urinary tract infections (UTI). More than 7 million UTI cases are annually diagnosed in the USA. Herewith, more than 2 million Americans with UTI are diagnosed with cystitis.
In late treatment of UTI, it is developed acute, chronic forms of the disease that may require hospitalization. In clinic, expenses for the treatment of complicated UTI are significantly higher than the expenses of UTI treatment at home.
Therefore, timely diagnosis and beginning of UTI treatment allow not only to prevent severe infection, but also significantly to reduce the costs of infectious disease treatment.
For the treatment of UTI in children and adults, it is used antibiotics included in different pharmacological groups. Many antibiotics for UTI are commercially available for several decades, but some went on sale just a few years ago.
Before prescribing antibiotic for UTI, the physician should determine the causative agent of infectious disease. In this regard, clinical examination and urine analysis are required. In frequent relapses of UTI, the doctor can prescribe antibiotic before the results of laboratory tests.
The duration of using antibiotics for UTI depends on the disease severity. In the treatment of severe UTI, the duration of antibacterial therapy can be a few weeks.
1. Acute UTIs (acute cystitis included)
One of the antibiotics that can be used only for the treatment of acute uncomplicated UTI is Nitrofurantoin. This oral antibiotic is approved by the FDA and is sold in the USA under the proprietary names Furadantin, Furalan, Ivadantin.
Nitrofurantoin is effective when treating UTI caused by pathogenic bacteria – Staphylococcus saprophyticus or Escherichia coli. For the treatment of acute UTI in children aged 12 years and older, a single dose of Nitrofurantoin 100mg should be taken within 7 days.
2. Complicated and uncomplicated UTIs
The FDA-approved antibiotic – Aztreonam is effective in the treatment of uncomplicated and complicated UTI caused by Escherichia coli, Klebsiella oxytoca, Enterobacter cloacae, Klebsiella pneumoniae, Citrobacter species, Pseudomonas aeruginosa, Serratia marcescens, and Proteus mirabilis.
Advantage of Aztreonam monobactam antibiotic lies in a broad-spectrum of antibacterial activity. However, given that Aztreonam should be administered as an intermittent intravenous infusion only, therefore at home this antibiotic for the treatment of UTI is used in rare case.
The maximum single dose of Aztreonam is 1 g, but the maximum frequency of use – 3 times a day. You can buy antibiotics for the complicated and uncomplicated UTIs containing antibacterial agent – Aztreonam under the trade names Cayston and Azactam.Read More
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